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<div class="content-intro"><p><strong><span data-contrast="auto">About Us</span></strong><span data-ccp-props="{}"> </span></p>
<div data-olk-copy-source="MessageBody">Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.<br><br></div>
<div>It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.</div>
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<div>Led by Tassos Gianakakos, Jay Edelberg, <span data-olk-copy-source="MessageBody">M.D., Ph.D.,</span> and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.</div>
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<div>We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.</div>
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<div>At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. <strong>Driven by patients and their families</strong>, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in <strong>being authentic</strong>—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an <strong>eagerness to learn</strong>, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to <strong>winning as a team</strong> with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to <strong>enable the impossible</strong> because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.</div>
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<div>These values are the foundation of our work, empowering us to make a real difference, every day.</div>
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<div> </div></div><p>Reporting to the <strong>Senior Director, Head of Planning</strong>, the <strong>Director, Demand & Supply Planning</strong> will lead execution of integrated demand, supply, inventory, and planning processes across Kardigan’s outsourced manufacturing and clinical supply network.</p>
<p>You will work closely with teams across Technical Operations, CMC, Clinical Operations, Quality, Regulatory Affairs, Finance, Procurement, Program Management, External Manufacturing, Clinical Supply Chain, and external partners. This role is a great fit for someone who enjoys bringing structure to ambiguity, connecting strategy to execution, and using data to help teams make smart decisions in a fast-moving clinical development environment.</p>
<p><strong>What You’ll Do</strong></p>
<ul>
<li>Build demand plans that translate clinical enrollment assumptions, protocol requirements, regional plans, and future launch expectations into practical forecasts.</li>
<li>Create integrated supply plans across drug substance, drug product, packaging, labeling, testing, release, distribution, and clinical supply activities.</li>
<li>Help ensure patients and clinical sites have the supply they need by balancing service, continuity, shelf life, and inventory investment.</li>
<li>Track inventory health, supply plan performance, forecast accuracy, capacity constraints, and emerging risks before they become issues.</li>
<li>Partner with External Manufacturing and Technical Operations to align CDMO execution activities with approved demand and supply plans.</li>
<li>Lead scenario planning for demand changes, manufacturing delays, batch outcomes, inventory needs, capacity availability, and launch readiness.</li>
<li>Turn complex planning data into clear recommendations, dashboards, and decision points for cross-functional planning and governance forums.</li>
<li>Improve how planning gets done by strengthening templates, assumptions, reporting cadences, data quality, and planning tools.</li>
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<p><strong>What You’ll Bring</strong></p>
<ul>
<li>10+ years for Director level in supply chain planning, demand planning, supply planning, clinical supply, manufacturing planning, or related operations roles.</li>
<li>Experience in biotechnology, pharmaceutical, medical device, or another regulated life sciences environment.</li>
<li>Strong understanding of clinical-stage supply chains, outsourced manufacturing networks, CDMO/CMO coordination, and planning across drug substance, drug product, packaging, labeling, testing, release, and distribution.</li>
<li>Ability to build forecasts, supply plans, inventory scenarios, planning dashboards, and data-driven recommendations that support cross-functional decisions.</li>
<li>Clear communicator who can influence without direct authority and partner effectively with technical, operational, financial, clinical, and executive stakeholders.</li>
<li>Bachelor’s degree in Supply Chain, Operations Management, Engineering, Life Sciences, Business, or a related discipline required; advanced degree, MBA, or APICS/ASCM certification preferred.</li>
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<p><strong>Preferred Experience</strong></p>
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<li>Experience in a clinical-stage, pre-commercial, launch-stage, or rapidly scaling biotech/pharma organization.</li>
<li>Experience supporting S&OP, Integrated Business Planning, long-range planning, or supply governance processes.</li>
<li>Experience with ERP, planning, inventory visibility, IRT, dashboarding, or analytics tools.</li>
<li>Comfort operating in a fast-paced, matrixed environment where priorities evolve and processes are still being built.</li>
</ul>
<p> </p><div class="content-pay-transparency"><div class="pay-input"><div class="description"><p>Exact Compensation may vary based on skills, experience and location.</p></div><div class="title">Pay range</div><div class="pay-range"><span>$203,000</span><span class="divider">—</span><span>$264,000 USD</span></div></div></div>